Dietary Grape Powder Inhibits Atopic Dermatitis-Like Skin Lesions in NC/Nga Mice

April 2019 in “ Journal of Investigative Dermatology ”

Chandra K. Singh, Charlotte A. Mintie, Mary A. Ndiaye, Gagan Chhabra, Susmit Singha Roy, Ruth Sullivan, B. Jack Longley, Stefan M. Schieke, Nihal Ahmad

atopic dermatitis dietary grape powder skin lesions acanthosis mast cell infiltration lymphatic expansion hematopoietic expansion serum IgE levels cytokines chemokines acute phase response pathway signaling molecules AD GP skin thickening immune cells immune system expansion allergy antibodies immune proteins inflammatory proteins immune response pathway cell signaling

Studysummary This study suggests that dietary grape powder may reduce the severity of atopic dermatitis in a mouse model, highlighting its potential in both prevention and intervention settings.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer ·

View this study on jidonline.org →

Discuss this study in the Community →

Similar Research

5 / 1000+ results

research Atlantic Mackerel Is Protective in DSS-Induced Colitis Rat Models

June 2024 in “Current Developments in Nutrition”

This study found that a nutritional intervention in dogs can alleviate atopic dermatitis symptoms by modulating immune responses and altering skin microbiome composition, which includes reducing fungal diversity and the abundance of pathogenic species such as Malassezia pachydermatis.

research Efficacy and Potential Mechanisms of Naringin in Atopic Dermatitis

4 citations , October 2024 in “International Journal of Molecular Sciences”

In this study, topical naringin was found to significantly improve dermatitis severity and reduce inflammatory markers in a mouse model of atopic dermatitis, suggesting its potential as a therapeutic agent for this condition.

research 710 Use of mass spectrometry imaging and a full thickness 3D skin equivalent for evaluation of percutaneous absorption

April 2017 in “Journal of Investigative Dermatology”

This study found that retinoic acid and a retinol complex formulation showed different permeation and compound localization in a skin equivalent model, with unique lipid changes observed with only the retinol formulation.

research Anti-Allergic Effects of Fermented Red Ginseng Marc on 2,4-Dinitrochlorobenzene-Induced Atopic Dermatitis-like Mice Model

1 citations , March 2022 in “Applied Sciences”

This study found that fermented red ginseng marc alleviated atopic dermatitis-like symptoms in mice, demonstrating antioxidant and anti-inflammatory effects similar to those of dexamethasone.

research 708 SIG-1451: A topical anti-inflammatory new chemical entity for atopic dermatitis (AD)

April 2017 in “Journal of Investigative Dermatology”

In laboratory tests and mouse models, this study found that the novel IPC analog SIG-1451 may offer potent anti-inflammatory effects for treating allergic skin inflammation, potentially outperforming some current therapies in specific inflammatory phases.