Genome-Wide Differential Expression Profiles in Nevus Sebaceous Revealed Low Expression of CDKN2AIP and Construction of a ceRNA Network

    Xianhong Yang, Rui Qiao, Nana Ni, Qian Zhang, Ke Zhang, Xuebao Shao, Wei Cheng, Jianfang Sun, Yiqun Jiang, Xianhong Yang, Rui Qiao, Nana Ni, Qian Zhang, Ke Zhang, Xuebao Shao, Wei Cheng, Jianfang Sun, Yiqun Jiang
    TLDR CDKN2AIP gene is less active in nevus sebaceous, affecting related RNA networks.
    The study investigated the differential expression profiles of mRNA and lncRNA in nevus sebaceous (NS) scalp tissues and identified a downregulated gene, CDKN2AIP, as a significant target among the differentially expressed mRNAs. Additionally, the researchers constructed a competing endogenous RNA (ceRNA) network involving CDKN2AIP and differentially expressed lncRNAs, providing insights into the molecular mechanisms underlying NS.
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