TLDR CDKN2AIP gene is less active in nevus sebaceous, affecting related RNA networks.
The study investigated the differential expression profiles of mRNA and lncRNA in nevus sebaceous (NS) scalp tissues and identified a downregulated gene, CDKN2AIP, as a significant target among the differentially expressed mRNAs. Additionally, the researchers constructed a competing endogenous RNA (ceRNA) network involving CDKN2AIP and differentially expressed lncRNAs, providing insights into the molecular mechanisms underlying NS.
10 citations
,
February 2019 in “Journal of Cellular Biochemistry” Specific RNA patterns are linked to alopecia areata.
11 citations
,
April 2017 in “Journal of The European Academy of Dermatology and Venereology” Found different long non-coding RNAs in balding Chinese men, which may help create new treatments.
854 citations
,
February 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” Understanding hair follicle development can help treat hair loss, skin regeneration, and certain skin cancers.
1 citations
,
February 2016 in “Cell Transplantation” Hair follicles have a more inactive cell cycle than other skin cells, which may help develop targeted therapies for skin diseases and cancer.
April 2016 in “Journal of the American Academy of Dermatology” Dermoscopy helped correctly diagnose a skin condition that was previously misidentified as a different hair loss disease.
June 2025 in “Journal of General-Procedural Dermatology & Venereology Indonesia” Serial excision effectively removed a large scalp lesion with minimal scarring and no hair loss.
September 2023 in “International Journal of Community Medicine and Public Health” Different sebaceous gland diseases can be treated with medications, hormone therapy, or surgical methods.
7 citations
,
February 2021 in “Dermatologic Therapy” Sebaceous glands are involved in various skin disorders, some treatable with medications like finasteride and minoxidil.