Genetics of Polycystic Ovary Syndrome

    December 2016 in “ Asian Pacific journal of cancer biology ”
    Atekeh Bahadori, Afrouz Khazamipour, Dariush D. Farhud
    TLDR PCOS is a hereditary disorder that can lead to diabetes and heart disease if not treated early.
    Polycystic ovarian syndrome (PCOS) is a complex hereditary disorder affecting 6-10% of women of reproductive age, characterized by chronic anovulation, hyperandrogenism, and often associated with insulin resistance, hirsutism, and obesity. The exact cause of PCOS is unknown, but it is believed to be due to a combination of genetic and environmental factors that become evident at puberty. Many women with PCOS have elevated insulin levels, which may contribute to increased androgen production, leading to symptoms such as acne, excess hair growth, weight gain, and ovulation issues. Early diagnosis and treatment of PCOS is crucial to reduce the risk of long-term complications, including type II diabetes, hypertension, heart disease, and stroke.
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