Associations Between Single-Nucleotide Polymorphisms of RFC-1, GGH, MTHFR, TYMS, and TCII Genes and the Efficacy and Toxicity of Methotrexate Treatment in Patients with Rheumatoid Arthritis

    Jerzy Świerkot, Ryszard Ślężak, Paweł Karpiński … Piotr Wiland
    Studysummary This study found that certain gene polymorphisms, specifically MTHFR 677CC and GGH 401TT and CT genotypes, were associated with fewer adverse effects from methotrexate in rheumatoid arthritis patients.
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