Mesotherapy for Local Fat Reduction

This article describes mesotherapy, a technique involving small doses of compounds injected into the skin for cosmetic uses like aging skin and fat reduction, and provides no new clinical results.

This study concluded that both phosphatidylcholine alone and with organic silicium effectively reduced submental fat, achieving optimal results after three sessions with mild and temporary adverse effects.

This review discusses the evolution and studies of injection lipolysis for fat reduction, highlighting the need for more research to ensure patient safety and treatment efficacy; it reports no new clinical results.

This study reviewed various lipolytic agents for reducing submental fat and highlighted that while deoxycholic acid is FDA-approved, other compounds like phosphatidylcholine with deoxycholate lack cosmetic approval due to safety concerns. Understanding these agents' mechanisms and anatomy is crucial for safe fat reduction applications.

This review discusses the use of mesotherapy, highlighting its popularity and the lack of large, randomized controlled trials, and advises cautious use.