Pre-Clinical Evidence for the Efficacy of Tryptanthrin as a Potent Suppressor of Skin Cancer

    October 2019 in “ Cell Proliferation ”
    Mohan Shankar G., Vijai V. Alex, Amrutha Nisthul A. … Ruby John Anto
    Studysummary This study reported that tryptanthrin, a compound found in indigo naturalis, effectively suppresses non-melanoma skin cancer in mice by reducing inflammation, inhibiting cell proliferation, and blocking specific signaling pathways associated with tumor growth.
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    Research cited in this study 4

    1. Pre-Clinical Evidence for the Efficacy of Tryptanthrin as a Potent Suppressor of Skin Cancer Cell Proliferation · 2019
    2. Basal Cell Carcinomas in Mice Arise from Hair Follicle Stem Cells and Multiple Epithelial Progenitor Populations Journal of Clinical Investigation · 2011
    3. CD34 Expression by Hair Follicle Stem Cells Is Required for Skin Tumor Development in Mice Cancer Research · 2007
    4. Solid Basal Cell Epithelioma Possibly Originates From the Outer Root Sheath of the Hair Follicle PubMed · 1993