Uncommon Phenomenon: Co-Location of Frontal Fibrosing Alopecia and Vitiligo in a Male. Case Report

June 2022 in “ Revista del Hospital Italiano de Buenos Aires ”

Denys E. Peñaloza, Anamá Di Prinzio, Cecilia Navarro, Luis Daniel Mazzuoccolo

frontal fibrosing alopecia scarring alopecia vitiligo autoimmune disorders

TLDR A rare case of a man having both frontal fibrosing alopecia and vitiligo was reported.

A rare case was reported of a 58-year-old male patient with co-localization of frontal fibrosing alopecia and vitiligo. Frontal fibrosing alopecia is a scarring alopecia characterized by the recession of the frontotemporal hairline, primarily affecting postmenopausal Caucasian women and rarely men. The specific mechanisms of its development were still under study, with several hypotheses suggesting an association with other autoimmune disorders.

View this study on ojs.hospitalitaliano.org.ar →

Discuss this study in the Community →

Research cited in this study

7 / 7 results

research Oral Minoxidil Treatment for Hair Loss: A Review of Efficacy and Safety

59 citations , July 2020 in “Journal of The American Academy of Dermatology”

Oral minoxidil promotes hair growth but may cause side effects; needs monitoring.

research Genome-Wide Association Study in Frontal Fibrosing Alopecia Identifies Four Susceptibility Loci Including HLA-B*07:02

115 citations , March 2019 in “Nature Communications”

Frontal fibrosing alopecia is linked to four genetic areas, especially the HLA-B*07:02 allele.

research Frontal Fibrosing Alopecia: A New Autoimmune Entity?

6 citations , January 2019 in “Medical Hypotheses”

Frontal Fibrosing Alopecia might be an autoimmune disease.

research Frontal Fibrosing Alopecia: Review of Recent Case Reports and Case Series in PubMed

9 citations , August 2018 in “Journal der Deutschen Dermatologischen Gesellschaft”

Most patients with frontal fibrosing alopecia are middle-aged women, often have thyroid disease, and some treatments can help stabilize the condition.

research Antiandrogenic Drugs: A Therapeutic Option for Frontal Fibrosing Alopecia Patients

10 citations , March 2016 in “Journal of The American Academy of Dermatology”

Antiandrogenic drugs could be a good treatment option for frontal fibrosing alopecia.

research Frontal Fibrosing Alopecia and Vitiligo: Coexistence or True Association

31 citations , January 2016 in “Skin Appendage Disorders”

Frontal fibrosing alopecia and vitiligo might be linked, not just coincidental.

research Frontal Fibrosing Alopecia: A Multicenter Review of 355 Patients

339 citations , February 2014 in “Journal of The American Academy of Dermatology”

Most patients with frontal fibrosing alopecia are postmenopausal women, and treatments like finasteride and dutasteride can improve or stabilize the condition.

Related Community Posts Join

6 / 626 results

community Fibrosing alopecia in a pattern distribution

in Research/Science 14 upvotes 1 year ago

A user has been experiencing hair loss for 4 years, with treatments like minoxidil, finasteride, and various supplements proving ineffective. They were diagnosed with fibrosing alopecia in a pattern distribution, a condition that may require a combination of anti-inflammatory and hair growth treatments.

community Concerned About Asymmetrical Frontal Hair Loss and Recent Finasteride Use, Seeking Experiences

in General 155 upvotes 4 days ago

The user is experiencing asymmetrical hair loss at the frontal hairline and is concerned about potential conditions like frontal fibrosing alopecia. They have started using finasteride and pumpkin seed oil to address the issue.

community DUPA/Retrograde might not be DHT based...GET A BIOPSY QUICK or permanent Hair Loss!

in Research/Science 43 upvotes 11 months ago

DUPA and retrograde alopecia may not be solely DHT-based, and a biopsy is crucial for accurate diagnosis and treatment. Treatments mentioned include dutasteride, oral minoxidil, pioglitazone, clobetasol, calcipotriol, ketoconazole, and doxycycline, depending on the specific condition.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 1 year ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community I think I’ve finally found the reason for my hair loss

in Chat 98 upvotes 1 year ago

The user experienced hair loss since 2019 and tried finasteride, dutasteride, RU58841, and ketoconazole shampoo without success. A scalp biopsy showed scarring and inflammation from folliculitis, indicating chronic inflammation was affecting treatment effectiveness.

community Dutasteride Isn't Working? Get a Scalp Biopsy NOW

in Finasteride/Dutasteride 19 upvotes 11 months ago

Dutasteride may not be effective for everyone due to underlying issues, suggesting scalp biopsies for further diagnosis. Users discuss using higher doses of dutasteride, topical treatments, minoxidil, and pyrilutamide for hair loss management.

Similar Research

5 / 1000+ results

research Frontal Fibrosing Alopecia: A New Autoimmune Entity?

6 citations , January 2019 in “Medical Hypotheses”

Frontal Fibrosing Alopecia might be an autoimmune disease.

research Alopecia Areata Mimicking Frontal Fibrosing Alopecia

February 2021 in “Cureus”

A woman's hair loss was initially misdiagnosed as scarring hair loss but was actually a treatable autoimmune hair loss.

research Medical Comorbidities in Patients with Lichen Planopilaris: A Retrospective Case-Control Study

19 citations , April 2018 in “International Journal of Dermatology”

People with Lichen Planopilaris are more likely to have autoimmune diseases, especially Systemic Lupus Erythematosus, and less likely to have diabetes and some other common conditions.

research Frontal Fibrosing Alopecia: A Retrospective Clinical Review of 62 Patients with Treatment Outcome and Long-Term Follow-Up

102 citations , April 2014 in “International Journal of Dermatology”

The treatment helped reduce symptoms and stabilize the hairline in most patients with Frontal Fibrosing Alopecia, but hair regrowth was limited.

research Frontal Fibrosing Alopecia: An Observational Single-Center Study of 306 Cases

June 2023 in “Life”

The study concluded that Frontal fibrosing alopecia can affect younger people, is often missed in men, and may be autoimmune-related.