TLDR Finasteride and CPA-EE2 equally reduce hirsutism, but affect hormone levels differently.
The study compared the effectiveness of finasteride and a combination of cyproterone acetate (CPA) and ethinyl estradiol (EE2) in treating hirsutism in 40 women. Both treatments were equally effective in reducing hirsutism, but had different effects on hormone levels. Treatment with CPA plus EE2 significantly decreased serum total and free T, A, DHEAS, and DHT and increased SHBG levels, while finasteride significantly increased total T but reduced DHT levels. The study suggests that preventing the conversion of T to DHT by inhibiting 5 α-reductase activity could be a reasonable treatment in hirsutism.View this study on onlinelibrary.wiley.com →
All three treatments reduce hirsutism, but spironolactone works best long-term.
Finasteride effectively reduces hair growth in women with polycystic ovary syndrome or idiopathic hirsutism.
Low-dose finasteride effectively treats hirsutism, is safe, and cost-effective.
Flutamide reduces hair growth better but has more side effects.
Cyproterone acetate-estrogen most effective for hirsutism, but consider side effects and patient needs.
Finasteride effectively reduces hair growth in women with idiopathic hirsutism, but requires careful contraception during treatment.
Finasteride effectively treats hirsutism in women, but more research needed for long-term results.
Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.
Finasteride and CPA-EE2 equally reduce hirsutism, but affect hormone levels differently.
Cyproterone acetate plus ethinyl estradiol is generally more effective in treating hirsutism, but consider side effects and patient characteristics.