July 1993 in “Drugs
    David H. Peters, Eugene M. Sorkin
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    TLDR Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.
    The document discusses the use of finasteride in treating benign prostatic hyperplasia (BPH) by reducing DHT levels, resulting in prostate shrinkage and improved urinary flow rate and symptoms. It is well-tolerated, but can cause sexual dysfunction in a small proportion of patients. The recommended oral dosage is 5mg daily, but it is not indicated for use in women or children due to its dysmorphogenic effects on male offspring. Clinical trials showed that it was effective in reducing symptoms and improving urinary flow, but the improvement was slight compared to surgical intervention. Concerns about its potential to mask the detection of prostate cancer have not been confirmed by clinical trials.
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