Commentary on Clinical Use of Extracellular Vesicles in the Management of Male and Female Pattern Hair Loss: A Preliminary Retrospective Institutional Review Board Safety and Efficacy Study

    January 2022 in “ Aesthetic surgery journal
    Alfonso Barrera
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    Studysummary This study found that injections of extracellular vesicles derived from mesenchymal stem cells improved hair growth in over 50% of female and nearly 80% of male patients after six months. Our plain-language summary of this paper — not a Tressless recommendation.
    The study reviewed the use of extracellular vesicles (EVs) derived from human bone marrow mesenchymal stem cells as a treatment for male and female pattern hair loss. It involved 31 patients (22 females and 9 males) who received EV injections and were monitored for at least 6 months. Results showed hair growth improvement in over 50% of females and nearly 80% of males. The treatment was noted for its decreased immunogenicity due to its allogenic acellular nature. The commentary highlighted the need for further comparison of EVs with other treatments like platelet-rich plasma (PRP) and nano fat grafting to assess the longevity of hair growth improvements. The author disclosed no conflicts of interest or financial support related to the study.
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