Evaluation of Betulin for Hair Growth Promoting Activity in Rats

March 2024 in “ International journal of pharmaceutical chemistry and analysis (Print) ”

Vinay Vishnudas Sarode, Subash Chander Gautam

betulin hair growth testosterone minoxidil testosterone-induced alopecia cholesterol hair length Rogaine

TLDR Betulin may help treat hair loss caused by testosterone.

The study evaluated the effect of betulin on hair growth in 48 albino wistar rats aged 12-16 months, with hair loss induced by a 0.5 mg/kg dose of testosterone. Over 28 days, the rats were treated with varying concentrations of betulin (10 mg/kg, 20 mg/kg, and 40 mg/kg) administered orally, a topical application of minoxidil solution, and a combination of betulin (10 mg/kg) and 3% minoxidil. The results showed that betulin decreased levels of cholesterol and testosterone, and increased hair length, suggesting its potential effectiveness in treating testosterone-induced alopecia.

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