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This study found that betulinic acid inhibits hepatitis C virus replication by suppressing the NF-κB- and ERK1/2-mediated COX-2 pathway, suggesting its potential as a therapeutic supplement.

In this pilot study, researchers found that betulin did not conclusively inhibit hair loss or promote regrowth in patients with hypothyroidism when compared to placebo.

In this study, albino wistar rats with testosterone-induced alopecia showed improved hair growth when treated with betulin, evidenced by increased hair length and decreased cholesterol and testosterone levels.

This study used computational methods to explore the potential of betulinic acid from Ziziphus spina-christi in treating alopecia, suggesting its possible protective effects on hair follicles by enhancing genomic stability and reducing oxidative damage, meriting further experimental validation.

This study reviewed information from various sources to highlight the versatile uses of botulinum toxin beyond aesthetic treatments, noting its successful application in fields like neurology, urology, and psychiatry, while also emphasizing its off-label therapeutic potential.