Epithelial–Mesenchymal Plasticity and Endothelial–Mesenchymal Transition in Cutaneous Wound Healing
December 2022
in “
Cold Spring Harbor Perspectives in Biology
”
Research cited in this study
18 / 18 resultsresearch Wound Healing: Cellular Mechanisms and Pathological Outcomes
Better understanding of wound healing is needed to develop effective treatments for chronic wounds.
research Stem Cell Dynamics, Migration, and Plasticity During Wound Healing
Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.
research An Ovol2-Zeb1 Transcriptional Circuit Regulates Epithelial Directional Migration and Proliferation
The Ovol2-Zeb1 circuit is crucial for skin healing and hair growth by guiding cell movement and growth.
research Skin Cell Heterogeneity in Development, Wound Healing, and Cancer
Different types of skin cells play specific roles in development, healing, and cancer.
research Homeostasis, Regeneration, And Tumor Formation In The Mammalian Epidermis
Stem cells in the skin help with healing and can also lead to cancer.
research Accelerated Endothelial to Mesenchymal Transition Increased Fibrosis via Deleting Notch Signaling in Wound Vasculature
Disrupting Notch signaling in blood vessels increases scarring during wound healing in mice.
research Epithelial-To-Mesenchymal Transition in Cutaneous Wound Healing: Where We Are and Where We Are Heading
The document concludes that a better understanding of cell changes during wound healing could improve treatments for chronic wounds and other conditions.
research Defining Stem Cell Dynamics and Migration During Wound Healing in Mouse Skin Epidermis
Stem cells help heal wounds by rapidly dividing and migrating to the wound edge.
research Cell-Type-Specific Chromatin States Differentially Prime Squamous Cell Carcinoma Tumor-Initiating Cells for Epithelial to Mesenchymal Transition
Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.
research Epithelial–Mesenchymal Transition in Keloid Tissues and TGF-β1–Induced Hair Follicle Outer Root Sheath Keratinocytes
Keloid scars may form due to changes in skin cell characteristics and specific protein signaling.
research Epithelial Stem Cells And Implications For Wound Repair
Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.
research The Skinny on Slug: Roles in Epidermis and Skin Health
Slug is crucial for skin health, hair growth, and healing.
research Slug (Snai2) Expression During Skin and Hair Follicle Development
Slug (Snai2) helps regulate hair growth timing in mice.
research Wound Repair at a Glance
Wound healing is a complex, multi-phase process involving various cells and activities to repair skin damage.
research Building Epithelial Tissues From Skin Stem Cells
Skin stem cells help maintain skin health, grow hair, and heal wounds.
research Wnt-Dependent De Novo Hair Follicle Regeneration in Adult Mouse Skin After Wounding
Hair follicles can regrow in wounded adult mouse skin using a process like embryo development.
research Scratching the Surface of Skin Development
The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.