Enzymatic Dissociation and Identification of Hair Follicle Stem Cells for Reversing Miniaturization in Androgenetic Alopecia

This study explored a method for enzymatic dissociation of hair-follicle-derived stem cells (HFDSCs) to treat androgenetic alopecia (AGA). Involving 40 patients, with 20 receiving HFDSC injections and 20 as controls, the study used hair follicles from transplant procedures to isolate stem cells. The test group showed a 19% improvement in hair density and a 20% improvement in hair caliber, with significant photographic improvements, while the control group showed deterioration. Although promising, the study highlights the need for further research, including larger multicenter randomized studies, to confirm the safety and efficacy of this treatment.