Enzymatic Dissociation and Identification of Hair Follicle Stem Cells for Reversing Miniaturization in Androgenetic Alopecia

    May 2025 in “ International Society of Hair Restoration Surgery ”
    Anil Garg, Seema Garg
    Studysummary In this small, non-randomized study, researchers reported that injecting hair-follicle-derived stem cells into the scalps of androgenetic alopecia patients improved hair density and caliber compared to a control group, suggesting potential efficacy of this approach; however, larger, randomized studies are needed to confirm these findings.
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    Research cited in this study 3

    1. Autologous Cell-Based Therapy for Male and Female Pattern Hair Loss Using Dermal Sheath Cup Cells: A Randomized Placebo-Controlled Double-Blinded Dose-Finding Clinical Study Journal of The American Academy of Dermatology · 2020
    2. Stem Cells from Human Hair Follicles: First Mechanical Isolation for Immediate Autologous Clinical Use in Androgenetic Alopecia and Hair Loss Stem cell investigation · 2017
    3. Characterization and Isolation of Stem Cell-Enriched Human Hair Follicle Bulge Cells ˜The œJournal of clinical investigation/˜The œjournal of clinical investigation · 2005

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