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GlossaryHair Follicle Stem Cells (HFDSCs)

specialized cells in hair follicles that regenerate hair and skin

Hair Follicle Stem Cells (HFSCs) are specialized cells located in the bulge region of hair follicles. They play a crucial role in the growth and regeneration of hair by periodically activating to produce new hair shafts and contribute to the repair of skin injuries. These cells have the unique ability to self-renew and differentiate into various cell types, making them essential for maintaining healthy hair and skin.

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research Hair Sciences: Hair Follicle Dermal Stem Cells

September 2015 in “International Society of Hair Restoration Surgery”

Hair follicle stem cells could lead to new hair loss treatments.

research Hair Follicle Dermal Stem Cells Regenerate the Dermal Sheath, Repopulate the Dermal Papilla, and Modulate Hair Type

184 citations, November 2014 in “Developmental Cell”

Hair follicle dermal stem cells are key for regenerating parts of the hair follicle and determining hair type.

research Platelet-Derived Growth Factor Signaling Modulates Adult Hair Follicle Dermal Stem Cell Maintenance and Self-Renewal

37 citations, April 2017 in “npj Regenerative Medicine”

PDGF signaling is crucial for maintaining and renewing hair follicle stem cells, which could help treat hair loss.

research A Bald Statement: Current Approaches to Manipulate Miniaturization Focus Only on Promoting Hair Growth

30 citations, May 2018 in “Experimental Dermatology”

The conclusion is that future hair loss treatments should target the root causes of hair thinning, not just promote hair growth.

research Hair Follicle Dermal Stem Cells and Skin-Derived Precursor Cells: Exciting Tools for Endogenous and Exogenous Therapies

30 citations, April 2017 in “Experimental Dermatology”

Hair follicle stem cells and skin cells show promise for hair and skin therapies but need more research for clinical use.

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community redensyl - follicle stem cell activator any experiences?

in Question 9 upvotes 7 years ago

A Swiss product called Redensyl, which is supposed to target hair follicle stem cells and has recently been marketed in Europe. The post inquires if anyone has had any experience with the product.

community TDM-105795 phase 2 results are in!

in Research/Science 28 upvotes 10 months ago

TDM-105795 showed promising hair growth results, with higher efficacy than placebo and minimal side effects. It activates dormant hair follicle stem cells and may maintain gains without immediate loss, unlike minoxidil.

community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 42 upvotes 4 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.