Elevated Mammalian Target of Rapamycin Gene Expression in Acne Vulgaris Patients
January 2023
in “
Al-Azhar International Medical Journal /Al-Azhar International Medical Journal
”
Studysummary This study found that mTOR gene expression was significantly higher in individuals with acne vulgaris compared to healthy controls, suggesting its potential as a biomarker for acne prognosis and treatment response.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
The study investigated the expression of the mTOR gene in acne vulgaris patients compared to healthy controls. It included 50 acne patients and 50 age- and sex-matched healthy individuals. The results showed that mTOR gene expression was significantly higher in acne patients, with a fivefold increase compared to the control group. Although there was a positive but nonsignificant correlation between mTOR expression and the duration of acne, the findings suggest that mTOR could serve as a prognostic biomarker for acne severity and treatment response.
