Efficacy And Safety Of Ritlecitinib In Alopecia Areata: A Systematic Review And Meta-Analysis

    July 2024
    Shaikha Salah Alhaj, Amani AlFalasi, Mohamed Ahmed, Sajad Allami
    Studysummary This meta-analysis reports that ritlecitinib significantly improved hair growth in alopecia areata patients compared to placebo, although its potential requires further clinical exploration.
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    Research cited in this study 12

    1. Hair Loss Profiles and Ritlecitinib Efficacy in Patients with Alopecia Areata: Post Hoc Analysis of the Allegro Phase 2b/3 Study Dermatology and therapy · 2023
    2. Efficacy and Safety of Ritlecitinib in Adolescents with Alopecia Areata: Results from the ALLEGRO Phase 2b/3 Randomized, Double-Blind, Placebo-Controlled Trial Pediatric Dermatology · 2023
    3. A Plain Language Summary on Ritlecitinib Treatment for Adults and Adolescents with Alopecia Areata Immunotherapy · 2023
    4. Janus Kinase Inhibitors For Alopecia Areata JAMA network open · 2023
    5. Safety of Janus Kinase Inhibitors in Patients with Alopecia Areata: A Systematic Review Clinical drug investigation · 2023
    6. Efficacy and Safety of Ritlecitinib in Adults and Adolescents With Alopecia Areata: A Randomised, Double-Blind, Multicentre, Phase 2b–3 Trial The Lancet · 2023
    7. Adverse Events in Patients Treated With Jak-Inhibitors for Alopecia Areata: A Systematic Review JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology · 2023
    8. Epidemiological Trends in Alopecia Areata at the Global, Regional, and National Levels Frontiers in immunology · 2022
    9. A Phase 2a Randomized, Placebo-Controlled Study to Evaluate the Efficacy and Safety of the Oral Janus Kinase Inhibitors Ritlecitinib and Brepocitinib in Alopecia Areata: 24-Week Results Journal of the American Academy of Dermatology · 2021
    10. JAK Inhibitors for Alopecia Areata: A Systematic Review and Meta-Analysis JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology · 2019
    11. Alopecia Areata: A Comprehensive Review of Pathogenesis and Management Clinical Reviews in Allergy & Immunology · 2017
    12. Epidemiology and Burden of Alopecia Areata: A Systematic Review Clinical, Cosmetic and Investigational Dermatology · 2015

    Related research 1

    1. Twenty Nail Dystrophy with Alopecia Areata in an Atopic Child International journal of research in dermatology · 2019