Evaluation of the Efficacy and Safety of Topical and Oral Treatment in Androgenetic and Hormonal Alopecia

    Jeanet Espinosa Bautista, Juan Carlos Rentería Covarrubias, José Antonio Alejo García
    TLDR The treatment effectively promoted hair growth with minimal side effects.
    This study evaluated the efficacy and safety of topical minoxidil combined with oral finasteride and dutasteride for treating androgenetic alopecia over 65 weeks. It was a non-randomized, unblinded clinical trial involving sequential photographic assessments and digital image analysis. Results showed that only 3 out of 44 patients (6.8%) did not experience significant changes, indicating the treatment's effectiveness in promoting new hair growth. Regarding safety, only one patient reported sexual dysfunction, which was further investigated. The study concluded that the combination treatment was effective and provided quantitative data for comparing patient groups, with no statistically significant differences found between them.
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