The Effectiveness and Safety of Three Treatment Regimens of Topical Minoxidil 5%, Betamethasone 0.064%, and Castor and Jojoba Oils for Alopecia Areata: A Multicenter Cohort Study

    January 2025 in “ Dermatologic Therapy ”
    Agus Abadi, Wala Abdeljawad, Emad Khatib … Basma Damiri
    Studysummary In this study, the combination of topical minoxidil and betamethasone was found to be more effective for hair regrowth and patient satisfaction in alopecia areata patients compared to betamethasone alone or with herbal oils, though further randomized trials are recommended.
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    Research cited in this study 27

    1. A Comparative Study on the Efficacy and Safety of 10% Topical Minoxidil Versus 5% Topical Minoxidil in the Treatment of Male Pattern Hair Loss QJM · 2024
    2. Degree of Alignment Between Japanese Patients and Physicians on Alopecia Areata Disease Severity and Treatment Satisfaction: A Real-World Survey Dermatology and therapy · 2023
    3. Alopecia Areata: An Updated Review for 2023 Journal of Cutaneous Medicine and Surgery · 2023
    4. Alopecia Areata: Diagnostic and Therapeutic Recommendations of the Polish Society of Dermatology. Part 2: Treatment Przegląd Dermatologiczny · 2023
    5. Comparison of Efficacy, Safety, and Satisfaction of Latanoprost Versus Minoxidil, Betamethasone, and in Combination in Patients with Alopecia Areata: A Blinded Multiple Group Randomized Controlled Trial Dermatologic Therapy · 2022
    6. Treatment Patterns and Treatment Satisfaction Among Adults With Alopecia Areata in the United States Advances in Therapy · 2022
    7. Evaluation of Fractional Carbon Dioxide Laser Alone Versus Its Combination With Betamethasone Valerate in Treatment of Alopecia Areata: A Clinical and Dermoscopic Study Archives of dermatological research · 2022
    8. Patient Perspectives of the Social, Emotional and Functional Impact of Alopecia Areata: A Systematic Literature Review Dermatology and Therapy · 2021
    9. Minoxidil for Patchy Alopecia Areata: Systematic Review and Meta-Analysis Journal of The European Academy of Dermatology and Venereology · 2019
    10. The Role of Vitamins and Minerals in Hair Loss: A Review Dermatology and Therapy · 2018
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    12. Factors Associated With Severity Of Alopecia Areata Annals of Dermatology · 2017
    13. Platelet-Rich Plasma Versus Minoxidil 5% in Treatment of Alopecia Areata: A Trichoscopic Evaluation Dermatologic Therapy · 2016
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    17. Utility of Dermoscopy in Alopecia Areata Indian Journal of Dermatology/Indian journal of dermatology · 2011
    18. Coudability Hairs: A Revisited Sign of Alopecia Areata Assessed by Trichoscopy Clinical and experimental dermatology · 2010
    19. Efficacy of Combination Therapy for the Management Regime of Alopecia Areata PubMed · 2007
    20. Drug Reactions Affecting Hair: Diagnosis Dermatologic Clinics · 2007
    21. A Randomized, Placebo-Controlled Trial of 5% and 2% Topical Minoxidil Solutions in the Treatment of Female Pattern Hair Loss Journal of The American Academy of Dermatology · 2004
    22. Efficacy of Betamethasone Valerate Foam Formulation in Comparison with Betamethasone Dipropionate Lotion in the Treatment of Mild-to-Moderate Alopecia Areata: A Multicenter, Prospective, Randomized, Controlled, Investigator-Blinded Trial International Journal of Dermatology · 2003
    23. A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men Journal of The American Academy of Dermatology · 2002
    24. Treatment of Chronic Severe Alopecia Areata with Topical Diphenylcyclopropenone and 5% Minoxidil: A Clinical and Immunopathologic Evaluation Journal of The American Academy of Dermatology · 1993
    25. Systemic Steroids With or Without 2% Topical Minoxidil in the Treatment of Alopecia Areata Archives of Dermatology · 1992
    26. 3 Percent Topical Minoxidil Compared With Placebo for the Treatment of Chronic Severe Alopecia Areata PubMed · 1988
    27. Topical Minoxidil in the Treatment of Alopecia Areata BMJ · 1983

    Related research 3

    1. Topical Minoxidil for the Treatment of Alopecia Areata PubMed · 2017
    2. Melasma in Men Journal of Pigmentary Disorders · 2015
    3. Effectivity of Minoxidil as a Treatment for Alopecia Areata DOAJ (DOAJ: Directory of Open Access Journals) · 2013