Degree of Alignment Between Japanese Patients and Physicians on Alopecia Areata Disease Severity and Treatment Satisfaction: A Real-World Survey

December 2023 in “ Dermatology and therapy ”

Kouki Nakamura, Kaeko Kamei, Jenny Austin, Simran Marwaha, James Piercy, Peter Anderson, Masayo Sakaki-Yumoto, Manabu Ohyama

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Studysummary This study observed that patient-physician alignment on alopecia areata severity largely followed Japanese Dermatological Association criteria, yet alignment on treatment satisfaction was lower, with lack of efficacy as the main dissatisfaction reason.

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research Integrated Safety Analysis of Baricitinib in Adults With Severe Alopecia Areata From Two Randomized Clinical Trials

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In this analysis, safety data from two clinical trials showed that baricitinib for severe alopecia areata had predictable side effects like infections and elevated CPK, with some serious adverse events noted at low incidence rates; no deaths were reported.

research Prevalence, Comorbidities, and Treatment Patterns of Japanese Patients with Alopecia Areata: A Descriptive Study Using Japan Medical Data Center Claims Database

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This study found that the prevalence of alopecia areata in Japan increased from 2012 to 2019, with allergic diseases as common comorbidities and a need for more effective treatments, particularly for severe and pediatric cases.

research Monotherapy for Alopecia Areata: A Systematic Review and Network Meta-Analysis

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This study used a network meta-analysis to compare alopecia areata treatments, finding that intralesional corticosteroids are most effective for mild cases, while diphenylcyclopropenone ranks highest for moderate to severe cases; further research on oral tofacitinib is needed.

research Alopecia Areata: Current Situation and Perspectives

34 citations , October 2017 in “Archivos Argentinos De Pediatria”

This review discusses the clinical characteristics, diagnosis, and treatment of alopecia areata, exploring potential environmental, immunological, and genetic factors involved in its development, but reports no new research findings.

research The Changing Landscape of Alopecia Areata: The Therapeutic Paradigm

77 citations , June 2017 in “Advances in Therapy”

This review discusses recent advances and ongoing clinical trials in novel therapeutics for alopecia areata, despite the lack of current FDA-approved treatments for severe cases, and reports no new results.

research Clinical Severity Does Not Reliably Predict Quality of Life in Women With Alopecia Areata, Telogen Effluvium, or Androgenic Alopecia

86 citations , May 2011 in “Journal of The American Academy of Dermatology”

This study found that patients with alopecia perceive their hair loss as more severe than dermatologists do, and their own ratings of hair loss severity better reflect their quality of life impacts.

research The Pattern and Profile of Alopecia Areata in Singapore: A Study of 219 Asians

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This study found that among an Asian population with alopecia areata, commonly first episodes occurred before age 40, with severe cases linked to psychological effects and treatments showing significant regrowth.