TLDR Dutasteride for hair loss might increase the risk of a rare stroke type.
In 2020, a case study reported a 25-year-old male who developed Cerebral Venous Thrombosis (CVT), a rare cause of stroke, after using dutasteride for alopecia treatment. The patient had been taking 0.5 mg of dutasteride every other day for 9 months. He developed a headache 7 months into the treatment, and horizontal diplopia (double vision) occurred 1 month after the onset of the headache. Brain imaging showed thrombosis in the left sigmoid and transverse sinuses. His symptoms improved after discontinuing dutasteride and starting anticoagulation. This was the first reported case of CVT potentially caused by dutasteride use. The researchers suggested that the increased estrogen level due to dutasteride use might have caused the formation of a thrombus. They concluded that the risk of CVT should be considered when prescribing dutasteride for alopecia.
13 citations,
May 2017 in “The Journal of urology/The journal of urology” Dutasteride is as safe for the heart as finasteride.
1 citations,
August 2015 in “Journal of the Korean neurological association” A man had a rare stroke possibly due to taking finasteride, which might have increased his hormone levels causing a blood clot. His memory loss didn't fully recover even after stopping the medication.
7 citations,
January 2014 in “Rinshō shinkeigaku” Finasteride, a hair loss medication, may be linked to stroke in young men.
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December 2023 in “Life” PRP helps skin heal, possibly through special cells called telocytes.
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November 2020 in “International Journal of Molecular Sciences” Advanced therapies like gene, cell, and tissue engineering show promise for hair regrowth in alopecia, but their safety and effectiveness need more verification.
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July 2022 in “Frontiers in Pharmacology” Dutasteride may help protect neurons and reduce inflammation in Parkinson's disease.
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December 2010 in “The Journal of Sexual Medicine” Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.
35 citations,
April 2013 in “Sexual medicine reviews” 5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.