The Study of Consistent Properties of Gelatinous Shampoo with Minoxidil
March 2016
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Aktualʹnì pitannâ farmacevtičnoï ì medičnoï nauki ta praktiki
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Studysummary This study found that the gelatinous minoxidil 1% shampoo demonstrated thixotropic properties and mechanical stability, suggesting predictable long-term consistency and effective distribution on the scalp. Our plain-language summary of this paper — not a Tressless recommendation.
The study conducted by I. V. Gnitko, V. V. Gladishev, A. P. Lisyanskaya, and I. A. Biriuk in 2016 investigated the consistent properties of a gelatinous shampoo containing 1% minoxidil for the complex therapy and prevention of alopecia. The shampoo was selected based on physical-chemical, biopharmaceutical, and microbiological investigations. The researchers found that the shampoo had exceptional thixotropic composition, meaning it could restore its consistency after mechanical loads, predicting stability during long-term storage. The dynamic flowing factors of the foam detergent gel with minoxidil (Кd1=38.9%; Kd2=78.06%) confirmed a sufficient degree of distribution when applied to the scalp or during manufacturing operations. The insignificant difference in "mechanical stability" between the gelatinous minoxidil 1% shampoo and its base indicated no interactions between the active substance and the base.
