Cognitive Effects of Testosterone and Finasteride Administration in Older Hypogonadal Men
August 2014
in “
DOAJ (DOAJ: Directory of Open Access Journals)
”
New to Finasteride? There is a guide in the encyclopedia. Read the guide → Studysummary This study reported that administering a supraphysiological dose of testosterone for one year resulted in minor cognitive benefits and decreased depressive symptoms in older hypogonadal men, but major cognitive improvements were not observed. Our plain-language summary of this paper — not a Tressless recommendation.
The study investigated the cognitive effects of administering testosterone and finasteride to 60 older hypogonadal men over 1 year. Participants were aged 60 years or older with low serum testosterone levels. They received testosterone-enanthate and finasteride in a 2x2 factorial design. Results showed that testosterone led to a small decrease in depressive symptoms and a moderate improvement in visuospatial memory. Finasteride slightly improved performance on a specific cognitive test. However, no major cognitive improvements were observed with either treatment. The study suggested that further research is needed to explore the potential cognitive benefits of testosterone replacement in other areas.
