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GlossaryHypogonadism

condition where sex glands produce insufficient hormones

Hypogonadism is a medical condition where the body's sex glands, the testes in men and the ovaries in women, produce little or no hormones. This can lead to various symptoms such as reduced libido, infertility, and in some cases, hair loss. It can be caused by genetic factors, injury, or certain medical conditions, and often requires hormone replacement therapy for management.

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research Original Research—Endocrinology: Comparison of the Steady-State Pharmacokinetics, Metabolism, and Variability of a Transdermal Testosterone Patch Versus a Transdermal Testosterone Gel in Hypogonadal Men

38 citations, February 2005 in “The journal of sexual medicine”

The testosterone patch and gel are both effective, but they have different absorption patterns and effects on hormone levels.

research The Five-Year Effects of Testosterone Replacement Therapy on Lipid Profile and Glucose Tolerance Among Hypogonadal Men in Japan: A Case Control Study

6 citations, January 2020 in “The Aging Male”

Testosterone replacement therapy improved blood sugar and fat levels without raising prostate cancer risk in Japanese men with low testosterone.

research Clinical Improvements in Erectile Function and Mood in Hypogonadal Men Treated with 4.5% Nasal Testosterone Gel (Natesto)

February 2018 in “The Journal of Sexual Medicine”

Natesto nasal gel improves erectile function and mood in men with low testosterone within 30 days.

research Oral Testosterone With and Without Concomitant Inhibition of 5α-Reductase by Dutasteride in Hypogonadal Men for 28 Days

11 citations, December 2010 in “The Journal of Urology”

Taking oral testosterone with or without dutasteride increases testosterone levels and could be an effective treatment for low testosterone.

research New Biomarkers to Evaluate Hyperandrogenemic Women and Hypogonadal Men

14 citations, January 2018 in “Advances in Clinical Chemistry”

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

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community Debunking the "Adverse metabolic consequences of dutasteride"

in Research/Science 40 upvotes 3 years ago

Dutasteride is more effective than finasteride, has neuroprotective benefits, and may prevent acne. Despite initial concerns about metabolic effects, further research suggests it is safe for most users, especially if not hypogonadal.

community Starting finasteride with poor hormones

in Finasteride/Dutasteride 7 upvotes 2 years ago

A user with low testosterone and mild gyno is considering finasteride for hair loss. Others suggest consulting an endocrinologist first and share experiences of finasteride not worsening gyno.

community Topical Dutasteride - Non-Hormonal, Side Effect Free 5ARI?

in Treatments 372 upvotes 3 months ago

Topical dutasteride is suggested as a low side-effect treatment for hair loss, with a proposed dose of 0.025% 1ml/day. It is considered better than finasteride due to its even inhibition of DHT isoforms and lower systemic absorption.

community How’s my pre fin lab work. Age 40

in Chat 6 upvotes 5 months ago

A user shared their pre-finasteride lab results, including DHT, estradiol, testosterone, SHBG, prolactin, FSH, and LH levels. Another user responded, cautioning against making unsupported claims about side effects and recovery.

community Any other celebrities known to be taking finasteride ?

in Finasteride/Dutasteride 455 upvotes 6 months ago

The conversation discusses various celebrities who reportedly use hair loss treatments like finasteride and dutasteride. Users share their experiences and opinions on starting treatment, with some encouraging the original poster to consult a dermatologist and consider treatment before it's too late.

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