Células-tronco foliculares e aspectos histopatológicos cutâneos tardios após prolongada remoção de pêlos a laser

This study analyzed the long-term effects of laser hair removal on hair follicles and stem cells in 22 female patients, aged 20 to 45, who had undergone diode laser treatment. The research found significant histopathological changes in treated skin, including infundibular dilation, hyperkeratosis, and dermal fibrosis, compared to untreated controls. Despite the presence of stem cells in both treated and untreated groups, the study suggested that the physiological deficiency in molecular communication between bulge stem cells and follicular papilla, along with fibrosis, might prevent hair regrowth. The implications of these changes on follicular function in older age or under increased tissue activity remain uncertain.