Classification scale for male and female androgenetic alopecia.
February 1996
in “Clinical Pharmacology & Therapeutics”
TLDR Scale created to measure hair loss in men and women; MK-386 reduces acne; Niaspan treats dyslipidemia; minoxidil increases heart rate.
A classification scale for male and female androgenetic alopecia has been developed using a computer-aided photo-retouching system. A validation study was performed to determine the consistency of these instruments in evaluating degrees of hair coverage in females and males. Topical application of MK-386, an inhibitor of Sa-reductase type 1, was found to reduce sebum DHT without measurable systemic exposure, which may benefit acne. Niaspan, a new sustained-release form of niacin, was found to be a safe and effective treatment for dyslipidemia in patients with primary hyperlipidemia. Intravenous infusions of minoxidil were administered to untreated mild/moderate hypertensives to establish a concentration-hemodynamic response relationship, and significant increases in heart rate were found for serum concentrations exceeding 20 ng/mL.
View this study on onlinelibrary.wiley.com →
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