Cell-Free Therapies: The Use of Cell Extracts to Mitigate Irradiation-Injured Salivary Glands

    February 2023 in “ Biology ”
    Xinyun Su, Akshaya Upadhyay, Simon D. Tran, Zhengmei Lin
    Studysummary This review highlights the potential of cell-free therapies, particularly cell extracts, in addressing radiation-induced salivary gland damage from head and neck cancer treatment, emphasizing their practicality and safety compared to traditional therapies despite incomplete understanding of their bioactive components.
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    Research cited in this study 6

    1. Cell and Cell-Free Therapies in Osteoarthritis Biomedicines · 2021
    2. Small Extracellular Vesicles from Menstrual Blood-Derived Mesenchymal Stem Cells as a Novel Therapeutic Impetus in Regenerative Medicine Stem Cell Research & Therapy · 2021
    3. From Stem Cells Protection to Skin Microbiota Balance: Orobanche Rapum Extract, a New Natural Strategy Journal of cosmetic dermatology · 2018
    4. Mesenchymal Stem Cell Secretome: Toward Cell-Free Therapeutic Strategies in Regenerative Medicine International Journal of Molecular Sciences · 2017
    5. Hair Growth-Promoting Effect of Geranium Sibiricum Extract in Human Dermal Papilla Cells and C57BL/6 Mice BMC Complementary and Alternative Medicine · 2017
    6. Radiation-Induced Microvascular Injury as a Mechanism of Salivary Gland Hypofunction and Potential Target for Radioprotectors Radiation Research · 2016