Reshaped Commensal Wound Microbiome Via Topical Application of Calvatia Gigantea Extract Contributes to Faster Diabetic Wound Healing

    January 2024 in “ Burns & Trauma ”
    Xiaotong Ding, Chenxi Yang, Yue Li … Jun Chen
    Studysummary In this study on diabetic wound healing in mice, Calvatia gigantea extract accelerated wound recovery, reduced inflammation, and improved the microbiome's diversity, particularly enhancing Escherichia–Shigella bacteria presence.
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    Research cited in this study 3

    1. Commensal Microbiome Promotes Hair Follicle Regeneration by Inducing Keratinocyte HIF-1α Signaling and Glutamine Metabolism Science Advances · 2023
    2. The Wound Microbiome Cold Spring Harbor perspectives in biology · 2022
    3. Bacteria Induce Skin Regeneration via IL-1β Signaling Cell Host & Microbe · 2021