TLDR Microneedle patches could replace injections but need more development for better use in medicine.
Microneedle-based drug delivery systems showed promise as alternatives to hypodermic injections, offering controlled agent delivery with fewer side effects. However, challenges such as drug loading methods, drug stability, and retention time were noted. The study highlighted recent advancements in microneedle patches for drug delivery in both in vitro and in vivo settings, and discussed their impact on cellular mechanisms and immunization pathways. Despite the potential, further attention was needed on refining fabrication methods, materials, and instruments to enhance their application in human medicine.
26 citations
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61 citations
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June 2022 in “Journal of Controlled Release” Dissolving microneedles show promise for delivering medication through the skin but face challenges like manufacturing complexity and regulatory hurdles.
