Animal Models and Culture Methods in the Study of Hair Growth

The review highlighted the extensive research on hair follicle biology using animal models and culture methods. Studies on mice with natural mutations, transgenesis, and gene knock-outs have been instrumental in understanding hair cycle mechanisms. Culture models, which allow control over growth conditions, have been crucial for dissecting follicle cell function in hair diseases. Despite these advances, the fundamental understanding of follicle cycling remained elusive, presenting a significant challenge for future research. The review emphasized that the existing models and methods would be central to upcoming experiments aimed at unraveling these mechanisms.