TLDR Beard cells, unlike scalp cells, produce growth factors in response to testosterone, which may explain differences in hair growth.
The study concluded that androgen-dependent beard dermal papilla cells secreted autocrine growth factors in response to testosterone, unlike nonbalding scalp dermal papilla cells. Beard cells showed a significant increase in DNA synthesis and mitogenic activity when exposed to testosterone, suggesting a unique androgen response that could explain the androgen-induced enlargement of hair follicles in beard growth. This differential behavior highlighted the potential role of these factors in androgen-dependent hair disorders and the need for further research to identify the specific mitogenic factors involved.
Cited in this study
8 / 8 results
227 citations
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January 1998 in “Journal of Endocrinology” Cells from balding scalps have more androgen receptors than cells from non-balding scalps.
16 citations
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August 1996 in “The journal of experimental zoology/Journal of experimental zoology” Red deer hair cells offer a new way to study how hormones affect hair growth.
30 citations
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March 1996 in “British Journal of Dermatology” 173 citations
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July 1995 in “Biochemical and biophysical research communications” Male hormones promote hair cell growth by using a growth factor from nearby skin cells.
48 citations
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April 1995 in “PubMed” Testosterone helps beard and axillary hair cells grow by releasing growth factors from dermal papilla cells.
157 citations
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April 1994 in “Clinical endocrinology” Androgens can cause hair growth in some areas and hair loss on the scalp.
124 citations
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April 1992 in “Journal of Endocrinology/Journal of endocrinology” Beard hair follicles have more androgen receptors than non-balding scalp hair follicles.
34 citations
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December 1991 in “Annals of the New York Academy of Sciences” The conclusion is that small hair follicles cause baldness in macaques, and treatments like antiandrogens and minoxidil can prevent hair loss and promote regrowth.