What Controls Hair Follicle Cycling?

    August 1999 in “ Experimental dermatology
    Kurt S. Stenn, Ralf Paus
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    TLDR The control system for hair growth cycles is not well understood and needs more research.
    The document from August 1, 1999, discusses the limited understanding of the chronobiological control system that regulates the hair follicle cycling through its growth (anagen), regression (catagen), and resting (telogen) phases, despite over a century of research and recent advances in the molecular understanding of hair follicle morphogenesis. The author expresses surprise at the scarcity of theoretical concepts published on the control of hair follicle cycling, given the extensive literature on various aspects of hair growth control. The document emphasizes the importance of this question for both basic and clinical hair biology and calls for more systematic and serious exploration in this area.
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