Role of Androgen on Physiological Function of Pilosebaceous Unit

March 2021 in “ Bioscientia medicina ”

Inda Astri Aryani, Cayadi Sidarta Antonius, Suroso Adi Nugroho, Nopriyati

androgen testosterone dihydrotestosterone androgen receptors sebum production hair growth sebocytes sebaceous glands dermal papillae hair follicles DHT

TLDR Androgens like testosterone affect oil production and hair growth in skin and hair follicles.

The document from 2021 discussed the role of androgen, a steroid hormone, on the physiological function of the pilosebaceous unit, which is a sebaceous gland with hair follicles. The androgen, consisting of testosterone and dihydrotestosterone, is activated by androgen receptors and affects sebum production and hair growth. The androgen receptors are located on sebocytes in the sebaceous glands and in the dermal papillae of hair follicles.

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research Hormonal Effects on Hair Follicles

102 citations , July 2020 in “International journal of molecular sciences”

Hormones like testosterone and estrogen significantly affect hair growth and structure.

research Androgens in Women: Role in Androgen-Mediated Cutaneous Disorders

56 citations , October 2018 in “Journal of The American Academy of Dermatology”

Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.

research Clinical Biochemistry of Dihydrotestosterone

50 citations , February 2013 in “Annals of Clinical Biochemistry”

Understanding how DHT works is important for diagnosing and treating hormone-related disorders.

research Androgen Action on Human Skin – From Basic Research to Clinical Significance

147 citations , October 2004 in “Experimental dermatology”

Hormones like testosterone affect skin functions and can cause skin issues when in excess; treatments to manage these effects are only somewhat effective.