Investigating the Relationship Between Androgenetic Alopecia and Hair Shape, Color, and Thickness: A Case-Control Study

    April 2025 in “ Health Science Reports ”
    Afsaneh Sadeghzadeh‐Bazargan, Alireza Jafarzadeh, A. El Ayoubi, Masoumeh Roohaninasab, Sara Dilmaghani, S H Salehi, Azadeh Goodarzi
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    Studysummary In this case-control study, researchers observed that smoking and lighter hair color significantly increased the risk of developing androgenetic alopecia, with older individuals and women showing higher prevalence rates, while hair thickness and shape were not linked to increased alopecia risk. Our plain-language summary of this paper — not a Tressless recommendation.
    This case-control study involving 100 participants (50 with androgenetic alopecia (AGA) and 50 controls) examined the relationship between AGA and various factors such as hair characteristics, smoking, age, and gender. The study found that smoking significantly increased the risk of AGA, with smokers being more than twice as likely to develop the condition. Lighter hair colors were also associated with a higher prevalence of AGA, while hair thickness and shape showed no significant association. Additionally, females had a higher prevalence of AGA compared to males. The study suggests that smoking cessation could be a potential intervention to reduce AGA risk and highlights the need for further research to understand the complex mechanisms of AGA.
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