Alopecia Areata: Effects of Treatment with Upadacitinib - Two Case Reports

February 2026 in “ Clinical Cosmetic and Investigational Dermatology ”

Julia Młyńska, Dominika Mysiorska, Natalia Zdanowska, Agnieszka Owczarczyk-Saczonek

Alopecia Areata Upadacitinib JAK inhibitor sarcoidosis

TLDR Upadacitinib improves life quality for Alopecia Areata patients without worsening skin issues.

The document discusses two case reports on the treatment of Alopecia Areata (AA) with Upadacitinib, a JAK inhibitor. The early use of this treatment has shown to improve the quality of life for patients both physically and psychologically. Importantly, it does so without worsening the skin lesions associated with sarcoidosis, suggesting that Upadacitinib is a promising option for managing AA effectively.

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