Association Between Androgenetic Alopecia And Cardiovascular Diseases: A Genetic Correlation And Mendelian Randomization Study

March 2026 in “ Archives of Dermatological Research ”

Jing Zhang, Haolong Ran, Dezhao Bi, Zhiqian Gu, Xiyu Liang, Yang Zhao, Yanning Xue

androgenetic alopecia cardiovascular diseases genetic correlation Mendelian randomization UK Biobank FinnGen AGA CVD

TLDR People with androgenetic alopecia may have a higher genetic risk for cardiovascular diseases.

The study investigates the genetic correlation between androgenetic alopecia (AGA) and cardiovascular diseases (CVD) using Mendelian randomization. The authors utilized data from large consortia, including the UK Biobank and FinnGen, to explore potential causal relationships. The findings suggest a significant genetic overlap between AGA and CVD, indicating that individuals with AGA may have an increased genetic predisposition to cardiovascular conditions. This research highlights the importance of considering AGA as a potential marker for cardiovascular risk, emphasizing the need for further studies to understand the underlying mechanisms.

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