Use of Human Induced Pluripotent Stem Cell-Derived CD271+CD90+ Mesenchymal Stem Cells for the Generation of Hair Inductive Dermal Cells

September 2016 in “ Journal of dermatological science ”

Ophelia Veraitch, Yo Mabuchi, Yasushi Matsuzaki, Takashi Sasaki, Aki Tsukashima, Masayuki Amagai, Hideyuki Okano, Manabu Ohyama

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human induced pluripotent stem cells hiPSCs mesenchymal stem cells MSCs CD271+CD90+ dermal papilla cells DP cells hair follicle bioengineering hair follicle HF MSC markers DP marker genes growth factors minoxidil human keratinocytes fibroblasts hair follicle-like structures SCID mice drug discovery hair diseases regeneration of human HFs stem cells hair loss Rogaine keratinocytes

Studysummary This study suggests that human induced pluripotent stem cells can be used to generate dermal papilla equivalent cells, potentially aiding hair follicle regeneration and drug discovery for hair diseases.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer ·

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Related Research

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research Expression of Mesenchymal Stem Cell Marker CD90 on Dermal Sheath Cells of the Anagen Hair Follicle in Canine Species

6 citations , September 2009 in “European journal of histochemistry”

This study found that CD90+ stem cells with fibroblast-like morphology are present in the lower part of the anagen hair follicle in dogs.

research Expression of Mesenchymal Stem Cell Marker CD90 on Dermal Sheath Cells of the Anagen Hair Follicle in Canine Species

15 citations , September 2009 in “European Journal of Histochemistry”

This study found that CD90+ cells, resembling mesenchymal stem cells, are abundantly present in the lower part of anagen hair follicles in dogs.