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research Tissue Engineering and Regeneration of the Human Hair Follicle in Androgenetic Alopecia: Literature Review

4 citations , January 2022 in “Life”

This review examines current and potential tissue engineering strategies for hair follicle regeneration in androgenetic alopecia but does not provide new clinical results, highlighting the need for further research and development.

research Use of human induced pluripotent stem cell-derived CD271+CD90+ mesenchymal stem cells for the generation of hair inductive dermal cells

September 2016 in “Journal of dermatological science”

This study suggests that human induced pluripotent stem cells can be used to generate dermal papilla equivalent cells, potentially aiding hair follicle regeneration and drug discovery for hair diseases.

research 803 Taxane chemotherapy induces epigenetic changes and premature senescence in human scalp hair follicles

July 2024 in “Journal of Investigative Dermatology”

Taxane chemotherapy can cause permanent hair loss by damaging hair follicles and altering their DNA.

research Stem cells, organoids and their applications for human diseases: Special issue of BMB Reports in 2023

2 citations , December 2022 in “Journal of Biochemistry and Molecular Biology”

This review discusses the development and potential applications of organoids for human disease modeling and regenerative medicine but reports no new experimental results.

research Identification of a human type XVII collagen fragment with high capacity for maintaining skin health

June 2024 in “Synthetic and systems biotechnology”

In this study, researchers identified a collagen fragment, sample-1707, expressed in E. coli, which forms nanofibers and promotes blood clotting, osteoblast differentiation, and skin cell regeneration, making it a promising biomaterial for skin care, with a large-scale production yield of 600 mg/L.

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community Weed/THC effects on hair growth/hair loss, and vitality of organ-culture human follicle studies (research review)

4 upvotes 1 year ago

Cannabis and THC may have mixed effects on hair, with some studies suggesting potential negative impacts on hair growth in isolated hair follicles, but these results are hard to apply to living humans. Treatments like minoxidil and finasteride are commonly used for hair loss, and the effects of cannabis might be neutral or vary based on individual factors.

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Follistatin

What is follistatin, and how does it influence hair follicle growth and regeneration? Follistatin blocks activin and related growth-inhibiting proteins, which in laboratory and animal work is described as keeping hair follicles in their growth phase; the only verifiable human evidence is a single small 2011 phase 1 injection trial, so follistatin remains experimental and is not an approved hair-loss treatment.

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