Topical Latanoprost Acid for Female Androgenetic Alopecia: A Pilot Proof-Of-Concept Trial With Mechanistic Evidence of FP-Receptor Activation

    March 2026
    Adriana Rakowska, Małgorzata Dutkiewicz, Oliwia Zegrocka-Stendel … Katarzyna Koziak
    Studysummary In this study, topical latanoprost acid applied daily for 6 months increased hair count and improved trichoscopic markers among women with hair loss, suggesting its potential for treating female androgenetic alopecia, particularly at a 0.05% concentration.
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    Research cited in this study 11

    1. Anti-Androgen Therapy for the Treatment of Female Pattern Hair Loss: A Clinical Review of Current and Emerging Therapies Journal of the American Academy of Dermatology · 2025
    2. Trichoscopy of Androgenetic Alopecia: A Systematic Review Journal of clinical medicine · 2024
    3. Female Pattern Hair Loss: Therapeutic Update Anais Brasileiros De Dermatologia · 2023
    4. Telogen Effluvium: A Review of the Science and Current Obstacles Journal of Dermatological Science · 2021
    5. Evidence-Based Guideline for the Treatment of Androgenetic Alopecia in Women and Men – Short Version Journal of The European Academy of Dermatology and Venereology · 2017
    6. Yellow Dots in Trichoscopy: Relevance, Clinical Significance, and Peculiarities Anais Brasileiros de Dermatologia · 2017
    7. A Randomized Double-Blind Placebo-Controlled Pilot Study to Assess the Efficacy of a 24-Week Topical Treatment by Latanoprost 0.1% on Hair Growth and Pigmentation in Healthy Volunteers with Androgenetic Alopecia Journal of The American Academy of Dermatology · 2011
    8. Dermoscopy in Female Androgenic Alopecia: Method Standardization and Diagnostic Criteria International Journal of Trichology · 2009
    9. Prostanoid Receptors in Anagen Human Hair Follicles Experimental dermatology · 2007
    10. A Randomized, Placebo-Controlled Trial of 5% and 2% Topical Minoxidil Solutions in the Treatment of Female Pattern Hair Loss Journal of The American Academy of Dermatology · 2004
    11. Hypertrichosis and Increased Pigmentation of Eyelashes and Adjacent Hair in the Region of the Ipsilateral Eyelids of Patients Treated with Unilateral Topical Latanoprost American Journal of Ophthalmology · 1997