Finasteride

November 2020 in “ Reactions Weekly ”

finasteride androgenetic alopecia 5alpha-reductase inhibitors erectile dysfunction loss of libido numbness soreness of testicles depression Propecia male pattern baldness ED low libido

Studysummary Finasteride can cause lasting erectile dysfunction, low libido, and depression in some patients.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

A 24-year-old man experienced erectile dysfunction, loss of libido, numbness, soreness of testicles, and depression during treatment with finasteride for androgenetic alopecia. His symptoms persisted even after stopping the treatment and seeking medical help. A study published in the Journal of Sexual Medicine in 2011 reported similar adverse effects of 5alpha-reductase inhibitors therapy, including persistent diminished libido, erectile dysfunction, and depression in some patients.

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Adverse Side Effects of 5α-Reductase Inhibitors Therapy: Persistent Diminished Libido, Erectile Dysfunction, and Depression in a Subset of Patients

research Adverse Side Effects of 5α-Reductase Inhibitors Therapy: Persistent Diminished Libido, Erectile Dysfunction, and Depression in a Subset of Patients

223 citations , December 2010 in “The Journal of Sexual Medicine”

This review discusses persistent adverse effects of 5α‐reductase inhibitors, like diminished libido and erectile dysfunction, in some patients and highlights the need for patient discussions before therapy, especially for androgenetic alopecia.