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Testosterone Improves Antidepressant-Emergent Loss of Libido in Women: Findings from a Randomized, Double-Blind, Placebo-Controlled Trial

research Testosterone Improves Antidepressant‐Emergent Loss of Libido in Women: Findings from a Randomized, Double‐Blind, Placebo‐Controlled Trial

36 citations , January 2014 in “The Journal of Sexual Medicine”

This study found that transdermal testosterone significantly increased the frequency of satisfactory sexual events in women experiencing SSRI/SNRI-related loss of libido, but did not improve overall sexual self-rating scores.

Adverse Side Effects of 5α-Reductase Inhibitors Therapy: Persistent Diminished Libido, Erectile Dysfunction, and Depression in a Subset of Patients

research Adverse Side Effects of 5α‐Reductase Inhibitors Therapy: Persistent Diminished Libido and Erectile Dysfunction and Depression in a Subset of Patients

223 citations , December 2010 in “The Journal of Sexual Medicine”

This review discusses persistent adverse effects of 5α‐reductase inhibitors, like diminished libido and erectile dysfunction, in some patients and highlights the need for patient discussions before therapy, especially for androgenetic alopecia.

research Finasteride Treatment of Hair Loss in Women

29 citations , May 2010 in “Annals of Pharmacotherapy”

This review discusses the limited objective evidence for using finasteride in women with alopecia, suggesting that it could be considered for those who don't benefit from minoxidil, but reports no new clinical results.

research Integrated Lipidomics in the Secreted Phospholipase A2 Biology

11 citations , February 2011 in “International Journal of Molecular Sciences”

This article reviews sPLA2-mediated phospholipid metabolism using sPLA2 transgenic/knockout mice and lipid mass spectrometry, offering insights into the distinct roles of sPLA2 enzymes in various biological events.

research Persistent Sexual Side Effects of Finasteride for Male Pattern Hair Loss

185 citations , March 2011 in “The Journal of Sexual Medicine”

This study found that 94% of healthy men reported low libido and 92% reported erectile dysfunction as persistent sexual side effects after using finasteride for male pattern hair loss, with these effects lasting on average 40 months post-discontinuation.

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community Reduced libido + almost no morning erections after 1.5 years of topical finasteride + minoxidil — should I stop finasteride?

72 upvotes 1 week ago

A user experienced reduced libido and fewer morning erections after 1.5 years of using topical finasteride and minoxidil for hair loss. They are considering stopping finasteride due to these side effects and are seeking advice on whether their libido will return to normal and if minoxidil alone will maintain their hair density.

community All my Finasteride users out there that take Creatine. Does it cause hair loss? What’s your experience and how much were you taking?

5 upvotes 4 years ago

Finasteride users discuss the potential impact of creatine on hair loss and libido. Some report no change, while others notice increased hair thinning, suggesting mixed experiences.

community Hair loss journey from 01 24 to 06 25 / HT and 5ARI only

in Progress Pictures 123 upvotes 1 year ago

A 28-year-old male shares his hair loss journey, starting with a hair transplant in February 2024 and using finasteride, later switching to dutasteride in January 2025. He has not used minoxidil and is satisfied with the results, despite some side effects like temporary nipple pain and a spike in libido.

community I can’t believe the cure for hair loss costs like $35 A YEAR

in Chat 288 upvotes 5 months ago

Finasteride is effective and affordable for preventing hair loss but may cause side effects like low libido. Some users combine it with minoxidil for better results, while others consider alternatives like dutasteride due to side effects.

community Has anyone stabilized their hair loss on fin and then switched to RU?

4 upvotes 6 months ago

The conversation discusses switching from oral finasteride to topical RU58841 for hair loss, with concerns about hormonal effects and libido. Some users suggest alternatives like dutasteride, while others share mixed experiences with RU58841's effectiveness.

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Learn

7 / 801 results

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Dutasteride

Heavy duty finasteride that comes with higher risks

Dutasteride side effects: what the label and studies actually report The Avodart label reports impotence in 4.7% and decreased libido in 3.0% of men in the first six months (1.7% and 1.4% on placebo), with new reports falling after month six; those figures come from BPH trials in older men, and the hair-loss trials in younger men run only six months. The label and studies also flag a PSA drop of about half, a small rise in high-grade prostate cancer in one trial, an observational link to depression, and sexual effects that the label says may persist after stopping.

learn Overview

learn Estradiol

an estrogen promoting hair regrowth more commonly used in women

learn Platelet-Rich Plasma

Are Platelet results permanent, or does hair loss return once treatment stops? Hair loss typically returns after stopping PRP treatment, as effects are not permanent.

learn Vitamin B12

How can you tell if your hair loss is related to low Vitamin B12 levels? Hair loss may indicate low Vitamin B12 if accompanied by fatigue and anemia symptoms.

learn Hair Transplant

What is shock loss after a hair transplant? Shock loss is temporary hair shedding after a transplant, usually resolving in a few months.
What is shock loss? Shock loss is temporary hair shedding after transplantation, usually resolving in 1-4 months.

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