Pharmacological Strategies for Mitigating Cytarabine-Induced Multi-Organ Toxicity: A Scoping Review on Mechanisms, Efficacy and Clinical Implications

    June 2026 in “ Cancers
    Ioannis Konstantinidis, Sophia Tsokkou, Kali Makedou, Eleni Gavriilaki, Georgios Delis, Theodora Papamitsou
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    Studysummary This scoping review identifies various pharmacological agents and five key mechanistic strategies being studied in vivo to mitigate multi-organ toxicity caused by cytarabine, with apraglutide and N-acetylcysteine highlighted as promising candidates for clinical application.
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