Effectiveness of Plasmotherapy in Various Nosologies

July 2023 in “ Vrach ”

А. М. Morozov, V. K. Dadabaev, V. Kurkova, Svetlana Semenova, L. Potockaya, M. A. Belyak

plasma therapy PRP therapy platelet-rich plasma autologous plasma growth factors neocollagenesis angiogenesis stem cell proliferation tissue remodeling PRP

Studysummary In this review, researchers reported that plasma therapy, specifically PRP therapy, shows a high regenerative potential with low toxicity and beneficial effects like immunomodulation and soft tissue remodeling, suggesting its recommendation for broader clinical use based on most studies.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

The article reviews the effectiveness of Platelet-Rich Plasma (PRP) therapy, highlighting its regenerative, anti-inflammatory, and immunomodulatory effects due to the high concentration of platelets and growth factors. PRP promotes neocollagenesis, angiogenesis, stem cell proliferation, and tissue remodeling, with the use of autologous material reducing infection or allergic reaction risks. The review supports PRP's widespread clinical use due to its low toxicity and high regenerative potential.

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Research cited in this study

6 / 6 results

research Evaluation of Adding Platelet-Rich Plasma to Combined Medical Therapy in Androgenetic Alopecia

5 citations , January 2021 in “Journal of Cosmetic Dermatology”

This study found that adding platelet-rich plasma with microneedling to conventional medical treatment significantly increased hair density and diameter in androgenetic alopecia patients compared to medical treatment alone.

research Platelet-Rich Plasma: New Performance Understandings and Therapeutic Considerations in 2020

848 citations , October 2020 in “International Journal of Molecular Sciences”

This review discusses the potential of platelet-rich plasma applications in regenerative medicine and explores recent progress and challenges in translating non-clinical PRP findings into human treatments, but reports no new clinical results.

research Platelet-Rich Plasma in the Treatment of Alopecia Areata: A Review

15 citations , October 2020 in “Journal of Investigative Dermatology Symposium Proceedings”

This review discusses the potential use of platelet-rich plasma for treating alopecia areata but reports no new experimental findings, noting the need for standardized protocols and larger studies to evaluate its efficacy.

research Progress in the Use of Platelet-Rich Plasma in Aesthetic and Medical Dermatology

3 citations , August 2020 in “PubMed”

This review discusses the potential efficacy and applications of platelet-rich plasma in dermatology, highlighting its use in various skin conditions but reporting no new clinical results; the authors call for standardization of preparation and treatment methods.

research Autologous Activated Platelet-Rich Plasma (AA-PRP) and Non-Activated (A-PRP) in Hair Growth: A Retrospective, Blinded, Randomized Evaluation in Androgenetic Alopecia

44 citations , February 2020 in “Expert Opinion on Biological Therapy”

In this study, autologous non-activated platelet-rich plasma was associated with greater hair re-growth than autologous activated platelet-rich plasma over long-term follow-up.

research Platelet-Rich Plasma: The Journey So Far

18 citations , January 2020 in “Indian Dermatology Online Journal”

This review summarizes available evidence on the dermatological use of platelet-rich plasma, particularly noting its efficacy for androgenetic alopecia and skin rejuvenation, but highlights significant gaps due to limited high-quality studies.