Adaptive Gelatin Microspheres Enhanced Stem Cell Delivery and Integration With Diabetic Wounds to Activate Skin Tissue Regeneration

This study found that acellular dermal matrix scaffolds may facilitate full-thickness skin wound healing by promoting a pro-regenerative immune response through M2 macrophage polarization via the Lamtor1 pathway.

This study developed an all-natural hydrogel that promotes diabetic wound healing by converting pro-inflammatory M1 macrophages to anti-inflammatory M2 macrophages in a simple and biosafe manner.

In this study, the combination of conditioned medium from human adipose-derived stem cells and photobiomodulation significantly enhanced wound healing in type 2 diabetic rats compared to using either treatment alone, with particularly superior results in wound strength and new blood vessel formation.

This study found that combining platelet-rich plasma with adipose-derived mesenchymal stem cells significantly improved diabetic wound healing in rats by enhancing angiogenesis and modulating the Notch signaling pathway.

In this study, exosome-loaded hydrogels derived from skin precursor cells significantly improved wound healing in diabetic rats by enhancing angiogenesis, reducing inflammation, and promoting tissue repair.