1 citations
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June 2009 in “WakeSpace (Wake Forest University)” This study found that keratin biomaterials derived from human hair promoted significant motor function recovery and neuromuscular regeneration in animal models of peripheral nerve injuries.
January 2015 in “Elsevier eBooks” This review discusses the potential of stem cell-based therapies combined with artificial nerve grafts for improving recovery in animal models of severe peripheral nerve injury, highlighting the need for further research on their application to humans.
This study found that exosomes derived from hair follicle neural crest stem cells significantly promoted nerve regeneration in injured neurons, particularly when overexpressing miR-214-3p, which enhanced axon extension and motor function recovery in both in vitro and in vivo models.
10 citations
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September 2024 in “Neural Regeneration Research” This study found that using induced pluripotent stem cell-derived mesenchymal stem cells with acellular nerve allografts significantly improved axon regeneration and functional recovery in rats with sciatic nerve injuries, suggesting a promising approach for clinical nerve repair therapies.
August 2026 in “Mendeley Data” In this study, researchers explored how hair follicle neural crest stem cell-derived exosomes, particularly those carrying miR-214-3p, promote neurite outgrowth and aid peripheral nerve regeneration, supported by detailed in vitro and in vivo data on nerve repair and functional recovery in rat models.