The Dose-Response of Percutaneous Estradiol Implants on the Skeletons of Postmenopausal Women

Finasteride has no effect on the user's estradiol levels, and body fat may influence aromatization. The user is on testosterone replacement therapy and uses everyday injections to manage high RBC count, with plans to measure DHT, DHEA-S, and pregnenolone levels.

The conversation discusses using estradiol mesotherapy to replicate hormone replacement therapy results while minimizing systemic exposure. It also covers the use of Spironolactone cream, which reportedly has no systemic side effects, and the potential risks of using bicalutamide and Spironolactone in men.

The conversation discusses concerns about starting topical finasteride due to high estradiol levels and the potential risk of gynecomastia. Suggestions include using ultrasensitive estradiol tests and considering aromatase inhibitors like zinc, ZMA, or DIM supplements.

A 22-year-old with high estradiol levels is considering starting finasteride for hair loss. They have an upcoming endocrinologist appointment to discuss whether they should proceed with the treatment.

The user experienced high estradiol levels and side effects after stopping finasteride and is concerned about whether these hormonal imbalances are temporary. They are seeking advice on reversing the condition without starting new treatments due to hypersensitivity to finasteride.

The user experienced hair loss after adding estradiol (in ALPICORT E) to their finasteride and minoxidil regimen, which initially provided almost full regrowth. The doctor advised using estradiol for 3 months, but users questioned the rationale and suggested sticking with finasteride and minoxidil.