Composite Hydrogel Dressing with Drug-Release Capability and Enhanced Mechanical Performance

August 2025 in “ Biomacromolecules ”

Jie Yang, Fanlei Yang, Wenhao Xu, Xiuqin Yu, Zhaozhu Zheng, Xiaoqin Wang, Kaili Chen, Jia Yu, Gang Li

composite hydrogel dressing berberine silk fibroin microspheres Calotropis gigantea fibers sodium alginate neovascularization follicular proliferation collagen deposition hydrogel silk fibroin Calotropis gigantea

Studysummary This study presents a novel composite hydrogel dressing with berberine-loaded silk fibroin microspheres and Calotropis gigantea fibers, demonstrating enhanced antibacterial activity, mechanical strength, and wound healing capabilities in treating chronic and infected wounds.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer ·

View this study on pubs.acs.org →

Discuss this study in the Community →

Similar Research

5 / 1000+ results

research Composite HydrogelDressing with Drug-Release Capabilityand Enhanced Mechanical Performance

1 citations , August 2025 in “OPAL (Open@LaTrobe) (La Trobe University)”

This study presents a composite hydrogel dressing with berberine-loaded silk fibroin microspheres and Calotropis gigantea fibers that demonstrates effective antibacterial properties, enhanced mechanical strength, and promotes wound healing.

research Fiber-reinforced hydrogel dressings for enhanced herbal compounds delivery in accelerated diabetic wound healing

1 citations , May 2025 in “European Polymer Journal”

This study developed a multifunctional dressing with the MeGel-SFSR composition, which showed faster healing and better tissue regeneration in diabetic wounds compared to controls, by utilizing a herbal compound and enhanced mechanical support, promoting hair follicle regeneration, collagen deposition, reduced inflammation, and vascularization in vivo.

research Bio-macromolecules/modified-halloysite composite hydrogel used as multi-functional wound dressing

8 citations , January 2021 in “Smart materials in medicine”

This study found that a newly constructed composite hydrogel dressing, made from silk fibroin, chitosan, and halloysite, promoted hair follicle neogenesis, angiogenesis tissue regeneration, and scar reduction.

Functionalization of Cotton Nonwoven Dressings with Herbal Compound-Loaded PHBV Short Nanofibers and Gelatin Hydrogel Coating for Accelerated Diabetic Wound Healing

research Functionalization of Cotton Nonwoven Dressings with Herbal Compound-Loaded PHBV Short Nanofibers and Gelatin Hydrogel Coating for Accelerated Diabetic Wound Healing

September 2025 in “ACS Applied Materials & Interfaces”

In this study, composite dressings made from SP nanofibers, Megel hydrogel, and cotton nonwoven significantly accelerated wound healing in diabetic mice, achieving ∼98% closure within 18 days, while enhancing tissue regeneration and reducing inflammation.

research A sandwich-like silk fibroin/polysaccharide composite dressing with continual biofluid draining for wound exudate management

28 citations , September 2023 in “International Journal of Biological Macromolecules”

Animal experiments in this study demonstrated that a new sandwich-like fiber/sponge dressing design, which enhances wound healing through improved moisture management and faster exudate evaporation, resulted in more significant wound size reduction compared to commercial and control dressings.