In Vitro Skin Models for Pigmentary Disorders: From Reconstructed Tissues to Skin-on-a-Chip Platforms
August 2026
in “
Regenerative Biomaterials
”
vitiligo melasma post-inflammatory hyperpigmentation solar lentigines senile lentigines cutaneous pigmentary disorders in vitro models ex vivo explants co-cultures three-dimensional skin equivalents bioprinted constructs organoids skin-on-a-chip platforms human pigmentation processes disease-specific pathological processes therapeutic evaluation vascular integration immune integration New Approach Methodologies skin models pigmentation disorders 3D skin models skin chip
Studysummary This review examines human-relevant in vitro models for studying pigmentation disorders, identifying both challenges and advancements in replicating human pigmentation processes and disease-specific pathology in vitro.
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