Polyethylene Glycol Ornamented Small Intestinal Submucosa Biosponge for Skin Tissue Engineering

In this laboratory study, researchers developed a genipin-stabilized asymmetric PLA/gelatin scaffold that mimics skin architecture, supports fibroblast proliferation, and closes scratches effectively, suggesting its potential for epidermal-dermal regeneration and applications in sensing or drug delivery.

This research reported that a newly developed adhesive wound dressing (SIS/PAA/LAP) demonstrated higher tissue adhesion and burst strength compared to conventional products, and improved tissue repair outcomes in animal models, suggesting potential for enhanced wound healing applications.

This paper describes the development of unique hydrogel skin scaffolds from plant-derived polysaccharide mixtures that may offer improved biocompatibility and mechanical properties for use in artificial skin.

This study developed a bilayer bionic skin scaffold that mimics the skin's structure to resist microbial invasion and enhance wound healing, with in vivo animal studies showing improved collagen deposition, neovascularization, and hair follicle formation.

This study found that crosslinking buffalo gelatin with different methods can modify its properties and potential as a skin substitute, though double-crosslinking may increase immunogenicity slightly.