Ectopic Production of Hair Keratin Constitutes Rushton's Hyaline Bodies in Association with Hematogenous Deposits

    Kei Sakamoto, Rumana Khanom, Miwako Hamagaki, Akira Yamaguchi
    Studysummary This study suggests that Rushton’s hyaline bodies form through both epithelial changes leading to hair keratin production and hemorrhage supplying erythrocytic substances, resolving previous debates about their origin.
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    Research cited in this study 6

    1. The Keratins of the Human Beard Hair Medulla: The Riddle in the Middle ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2009
    2. The Catalog of Human Hair Keratins Journal of Biological Chemistry · 2001
    3. Transcription Regulation and Protein Subcellular Localization of the Truncated Basic Hair Keratin hHb1-ΔN in Human Breast Cancer Cells Journal of Biological Chemistry · 2001
    4. Keratin 17 Expression in the Hard Epithelial Context of the Hair and Nail, and Its Relevance for the Pachyonychia Congenita Phenotype Journal of Investigative Dermatology · 2000
    5. The Catalog of Human Hair Keratins Journal of biological chemistry/˜The œJournal of biological chemistry · 1999
    6. Expression of a Truncated Form of hHb1 Hair Keratin in Human Breast Carcinomas British Journal of Cancer · 1998

    Related research 2

    1. Structure and Site of Expression of a Murine Type II Hair Keratin Molecular Biology Reports · 1992
    2. Keratin 19: Predicted Amino Acid Sequence and Broad Tissue Distribution Suggest It Evolved from Keratinocyte Keratins Journal of Investigative Dermatology · 1989